SickKids Hospital

Toronto, Ontario

Description

The Hospital for Sick Children (SickKids) is one the largest hospital and research facility dedicated to childhood diseases in Canada and North America.  The  SickKids Garron Family Comprehensive Cancer Centre sees over 350 primary cancer cases per year including more than 100 new brain tumor patients, and  provides consultations for brain tumor patients worldwide. The dedicated multidisciplinary Pediatric Brain Tumor team is comprised of social workers, psychologists, rehabilitation specialists, neuro-radiologists, neuro-pathologists, 5 neuro-oncologists and 5  pediatric neurosurgeons who are all also deeply engaged in innovative  clinical trials and basic/translational research on childhood brain tumors. Many team members are laboratory scientists in the Arthur and Sonia Brain Tumor Research Centre - home to the MAGIC , Rare Brain Tumor and BMMRD international collaborative consortia, and are global leaders who have led critical scientific breakthroughs to advance diagnosis, classification and treatment of more common childhood brain tumors such as medulloblastoma and low grade gliomas, as well as rare cancers including CNS rhabdoid tumors/ATRTs, ETMRs and DIPG.  Some of the current areas of research include novel therapeutic approaches for high risk infant brain tumors, cognitive enhancement/preservation therapies, immuno- and targeted therapy for brain tumors, new methods of drug delivery and cancer stem cell therapeutics.

Housing Information

Ronald McDonald House Charities Toronto
240 McCaul Street
Toronto, ON, M5T 1W5
Canada

Contact information

 

555 University Ave
Toronto, ON, M5G 1X8

 

Phone: 416-813-7360
E-mail: Annie.huang@sickkids.ca

Team

Principal Investigator
Senior Neuro-Oncologist
Dr Huang is a neuro-oncologist in the Pediatric Brain Tumor program, senior scientist/principal investigator in the Cell Biology Program and the Arthur and Sonia Labatt Brain Tumor Research Center at the Hospital for Sick Children, and holds academic appointments as Professor of Pediatrics, Medical Biophysics, Lab Medicine and Pathobiology at the University of Toronto, Canada. Dr Huang’s clinical and research interest is in biology and innovative therapies for rare pediatric brain tumors, and brain tumors arising in infancy. She established and leads the Rare Brain Tumor Consortium (www.rarebraintumroconsortium.ca), a unique worldwide biorepository and clinical registry for rare brain tumors. Studies from her lab has helped to advance biological understanding and novel therapies for rare embryonal brain tumors including ETMRs, PNETs and ATRTs.
Co-Principal Investigator
Staff Neuro-Oncologist
Dr. Ute Bartels is a Staff Neuro-Oncologist at the Hospital for Sick Children, Toronto and Professor of Paediatrics at the University of Toronto. She graduated from medical school at Johannes Wolfgang von Goethe University in Frankfurt, Germany. Dr. Bartels completed her PhD thesis at the Children’s Hospital of the University in Mainz, Germany, where she trained in Paediatrics and specialized in neonatology and paediatric haematology/oncology. In 2002, she joined the Hospital for Sick Children for a fellowship in paediatric neuro-oncology and became a staff physician in 2005. She was/is the acting section head of the program during the director’s sabbatical in 2007-2008 and 2017-2018. Dr. Bartels received the Junior Faculty Award for Clinical Excellence in Paediatric Medical Care in 2009. She completed a Master of Science in Clinical Epidemiology at the University of Toronto in 2010. She is an active member of the Central Nervous System (CNS) Committee of the Children’s Oncology Group (COG) in North America and is a Principal Investigator of the CNS Germ Cell Tumour study (ACNS1123). She was an invited member of the 2012 International Tuberous Sclerosis Complex (TSC) Consensus Group to finalize diagnostic, surveillance and management recommendations for patients with TSC. She is elected co-chairwoman of the European Society of Paediatric Oncology (SIOPe) craniopharyngioma working group representing the field of oncology/endocrinology since 2011.