About

Mission Statement

To understand how brain tumors develop in children and identify personalized treatment strategies.


About PNOC

The Pacific Pediatric Neuro-Oncology Consortium (PNOC) was formed to provide children with brain tumors access to innovative treatments. What sets us apart is that we pursue clinical strategies that are based on the molecular and genetic make-up of each tumor. We test therapies aimed at interfering with specific cellular pathways or mutations after confirming that a patient’s tumor has those characteristics, sparing patients therapy that is not optimized for their tumor type. 

The teams at each of PNOC’s 15 participating hospitals are made up of specialists in different areas of pediatric brain tumor treatment – such as oncology, neurosurgery, and radiation therapy – who combine their expertise to optimize care for each patient. The teams also include nurses, social workers, and hospital staff with an in-depth understanding of the needs of families and children suffering from brain tumors. Finally, each site has scientists actively engaged in laboratory research on pediatric tumor biology who work with clinicians to turn their findings into therapies.


PNOC Scientific Committee

The Scientific Committee consists of designated key physicians and laboratory investigators at each of the Member Institutions. The goal of the Scientific Committee is to advise and assist in setting the scientific strategy of the PNOC. The members of the Scientific Committee play a critical role in developing the translational agenda, and assist and conduct pre‐clinical and laboratory studies as needed to support the development of study concepts and/or correlative studies linked to specific PNOC clinical trials.

Committee Members

Oren Becher, MD
Ann & Robert H. Lurie Children’s Hospital of Chicago (Lurie)

Rishi Lulla, MD, MS
Ann & Robert H. Lurie Children’s Hospital of Chicago (Lurie)
RLulla@luriechildrens.org

Girish Dhall, MD
Children's Hospital Los Angeles (CHLA)
GDhall@chla.usc.edu

Ashley Margol, MD
Children's Hospital Los Angeles (CHLA)
amargol@chla.usc.edu

Anat Epstein, MD, PhD
Children's Hospital Los Angeles (CHLA)
AEpstein@chla.usc.edu

Adam Resnick, PhD - CHAIR
Children's Hospital of Philadelphia (CHOP)
resnick@email.chop.edu

Angela Waanders, MD, MPH
Children's Hospital of Philadelphia (CHOP)
waandersa@email.chop.edu

Michael Fisher, MD
Children's Hospital of Philadelphia (CHOP)
fisherm@email.chop.edu

Brian Rood, MD
Children's National Medical Center (CNMC)
BROOD@childrensnational.org

Javad Nazarian, PhD
Children's National Medical Center (CNMC)
JNazarian@childrensnational.org

Yanxin Pei, PhD
Children's National Medical Center (CNMC)

Miriam Bornhorst, MD
Children's National Medical Center (CNMC)
Children’s Hospital & Research Center Oakland (CHRCO)
MBornhorst@childrensnational.org

Mimi Bandopadhayay, PhD
Dana-Farber Cancer Institute (DFCI)
pratiti_bandopadhayay@dfci.harvard.edu

Mark Kieran, MD
Dana-Farber Cancer Institute (DFCI)
mark_kieran@dfci.harvard.edu

Mohamed AbdelBaki, MD
Nationwide Children's (Nationwide)
Mohamed.AbdelBaki@nationwidechildrens.org

Dean Lee, MD, PhD
Nationwide Children's (Nationwide)
Dean.Lee@nationwidechildrens.org

Elaine Mardis, PhD
Nationwide Children's (Nationwide)
Elaine.Mardis@nationwidechildrens.org

Monika Davare, PhD
Oregon Health & Science University (OHSU)
davarem@ohsu.edu

Yoon-Jae Cho, MD
Oregon Health & Science University (OHSU)
chyo@ohsu.edu

Ibrahim Qaddoumi, MD, MS
St. Jude Children's Research Hospital (St Jude)
Ibrahim.Qaddoumi@stjude.org

Amar Gajjar, MD
St. Jude Children's Research Hospital (St Jude)
amar.gajjar@stjude.org

Rob Prins, PhD
University of California, Los Angeles (UCLA)
rprins@mednet.ucla.edu

Linda Liau, MD
University of California, Los Angeles (UCLA)
lliau@mednet.ucla.edu

Rob Wechsler-Reya, PhD
University of California, San Diego / Rady Children’s Hospital (UCSD/Rady)
rwreya@sbpdiscovery.org

Donald Durden, MD, PhD
University of California, San Diego / Rady Children’s Hospital (UCSD/Rady)
Ddurden@ucsd.edu

David Raleigh, MD, PhD
University of California, San Francisco (UCSF)
University of Utah (UTAH)
University of Washington / Seattle Children's (UW/Seattle)

Josh Rubin, MD, PhD
Washington University in St. Louis (WUSTL)
rubin_j@kids.wustl.edu

  • 98 Pediatric Brain Tumor Specialists
  • 5 active clinical trials
  • 15 participating
    sites
  • PI Spotlight

    Anthony C. Wang, MD
    Pediatric Neurosurgeon
    Dr. Wang is a pediatric neurosurgeon who specializes in the treatment of children with brain and spine tumors. He researches immunotherapy treatments for pediatric tumors and also studies their molecular and genetic characteristics.